What looks like rheumatoid arthritis, feels like rheumatoid arthritis, but isn’t rheumatoid arthritis? Palindromic rheumatism.

First described in 1944 as a "new, oft-recurring disease of joints" (Arch. Intern. Med. 1944;73:293-321), palindromic rheumatism is similar to rheumatoid arthritis in that its characteristic features include pain,... »

Overuse injuries are very common in children and teenagers, especially among kids who play sports throughout the year.

Although rare, primary systemic vasculitis in children is associated with significant mortality and morbidity when not properly treated. Optimal management of the group of multiorgan inflammatory conditions is hampered by the lack of... »

The role of corticosteroids in the treatment of rheumatoid arthritis has changed substantially since their introduction in the late 1940s. The powerful anti-inflammatory agent was initially perceived as a miracle drug because of its dramatic clinical effects in individuals with severe, debilitating disease. The fervor diminished as evidence of adverse... »

Lupus nephritis is the most important complication of systemic lupus erythematosus, as it is closely linked to survival and morbidity in patients with the autoimmune disease. It is also one of the most controversial, noted Dr. David R.W. Jayne. Recent data indicate that more than 40% of SLE patients who develop nephritis develop progressive kidney disease,... »

Positive outcomes in rheumatoid arthritis are closely associated with early diagnosis and treatment with disease-modifying antirheumatic drugs, Dr. Vivian Bykerk stressed at the annual European Congress of Rheumatology. “Several important studies have shown that early intervention can lead to optimal outcomes for patients with early inflammatory... »

Catastrophic antiphospholipid syndrome is a potentially fatal thrombotic disease that develops in a subset of patients with antiphospholipid syndrome. Survival of patients with the rare condition, which is characterized by the development of multiple organ thromboses over a short period of time, depends on the vigilance of the treating clinicians, early... »

Primary angiitis of the central nervous system in children, which encompasses a spectrum of progressive and nonprogressive large- and small-vessel inflammatory brain diseases, has been linked in recent years to a range of neurologic conditions, such as refractory status epilepticus, movement disorders, severe cognitive dysfunction, optic neuritis, and... »